Ryan Newman was left in a "serious condition" in hospital on Monday night following a devastating crash during the final lap of the Daytona 500.

Roush Fenway Racing driver Newman was leading the race in Florida with less than a lap remaining when he was spun out by Ryan Blaney, and subsequently thrown into the air as Corey LaJoie crashed into him at 190 miles-per-hour, according to Sky.

Newman's car landed on its roof and burst into flames, before rescue crews rushed to stop the fire and get the 42-year-old out of the vehicle. 

He was taken immediately to hospital, where doctors are treating him for serious but "non life threatening injuries."

"Ryan Newman is being treated at Halifax Medical Center," said NASCAR executive Steve O'Donnell after the incident.

"We appreciate your thoughts and prayers and ask that you respect the privacy of Ryan and his family at this time."

See the full sequence of events, and the aftermath, below.